Is it time to give up?

Is there really a point to all this? Is my purpose in life to help others and have no life in return? Business isn't going well, I have a major bank loan to pay without mentioning all other debts... Is this worth is?
I can't even afford my own personal bills right now.
Should I just give up and try to sell? What then?
There are good days and not so good ones, this is one of the really bad ones...
Bills to pay and no money, I can barely stand on my feet but have to work starting in the morning until late at night, weekends too... I'm getting sooo tired and feeling more and more lonely...
Is it worth it?
Not only does my work life push people away, right now so do I. I want a break from everything and don't know what to do about it, where to turn to. I just take refuge at work but I feel my body and mind overworked.
I feel like I am doing so many things wrong, I just don't know what they are...